When to start — and why "wait and relax" can cost you
The clinical convention is clear: evaluation is warranted after 12 months of regular attempts without conception — or after 6 months when the woman is 35 or older. It should begin immediately when there are known signals: very irregular or absent cycles, known tubal disease or endometriosis, prior pelvic surgery or infection, chemotherapy history, or a partner's known sperm issue.
Age is the one variable no treatment resets. That is not a reason for panic; it is a reason for timeliness. The most expensive advice in fertility is a comfortable "just relax and keep trying" given to the wrong couple for two more years.
And one rule this pathway never bends: fertility assessment evaluates the couple, not the woman. The male factor contributes in roughly half of cases; a semen analysis is a first-line test, not an afterthought when everything else is "fine."
What the core work-up actually contains
For her: cycle history read properly (length, regularity, pain, bleeding pattern); AMH and an antral follicle count by ultrasound as the two main reserve markers; confirmation of ovulation (mid-luteal progesterone); thyroid (TSH) and prolactin where indicated; and assessment of the tubes and uterus — typically an HSG (dye X-ray) or saline sonogram — because open tubes are a precondition for everything except IVF.
For him: a semen analysis by WHO standards — volume, concentration, motility, morphology — repeated once if abnormal, since values swing; DNA fragmentation testing in specific situations (we cover the depth of this in the Sperm Analysis pathway).
The consultation's real value is reading these together: an AMH result means one thing at 29 and another at 41; a borderline morphology means little alone and much beside a low count; "unexplained" is a real category with its own decision tree, not a dead end.